Schedule

Jenn Abelin
BROAD institute and Dana-Farber Cancer Institute, Boston, USA

Pavel Baranov
The EMBO Keynote Lecture
University College Cork, Ireland

Eric Deutsch
Institute for Systems Biology, Seattle, USA

Lennart Martens
Ghent University & VIB, Belgium

Eivind Valen
University of Oslo, Norway

Wu Wei
Singapore Immunology Network, A*STAR, Singapore

Zhi Xie
Sun Yat-sen University, China

Michal Bassani-Sternberg
Joint session speaker ncPP-HUPO HIPP
Ludwig Institute for Cancer Research / UNIL-CHUV, Lausanne, EU

Yardena Samuels
Joint session speaker ncPP-HUPO HIPP
Weizmann Institute of Science, Israel

Sonia Chothani
Genome Institute of Singapore, A*STAR, Singapore

Marie Brunet
Sherbrooke University, Canada

Please note that the program is tentative and subject to change. Exact timings and talk titles will be updated in due time.

S01: Foundation of RNA Translation & Ribo-seq

Lecture by Pavel Baranov, Foundations of RNA Translation and the Expanding Coding Landscape
Lecture by Eivind Valen, Ribo-Seq at Scale, Predicting Micropeptides from a Trillion Reads
Coffee Break

S02: Experimental Workflows and Pre-processing

Lecture by Zhi Xie, Translation databases and quality control
Hands-on Demo by Sonia Chothani, Pre-processing, ORF Detection and differential translation analysis
Networking & Singapore sightseeing / group activity

S03: Applications and Other Ribosome-associated Technologies

Lecture, Speaker/Title TBD
Sponsor Talk by Massimiliano Clamer, Immagina Biotech, Technology Solutions for Translation Profiling and Ribosome-associated Workflows
Flash Talks and Practical Session, Application-catered ORF Selection
Coffee Break

S04: Foundations and outlook of proteomics and immunopeptidomics

Lecture by Lennart Martens, Focus, but broadly: AI's role in the high dynamic range immunopeptidome
Lunch

S04: Proteomic Workflows for Non-canonical Protein Identification

Lecture by Eric Deutsch, High-quality Peptide Evidence for Annotating Non-canonical ORFs as Proteins
Lecture by Wu Wei, Immunopeptidomics: From Samples to Peptide Discovery
Coffee Break

S05: Spectral Validation for Confident Identification

Hands-on Demo by Marie Brunet, Targeted Proteomics for Rare Peptide Discovery and Quantitative Protein Dysregulation
Panel Discussion, What Evidence Is Enough for Confident ncPP Identification?
Speakers Dinner

Combined Event with ncPP and HIPP

09:00–09:30 Lecture by Jenn Abelin, Dark Proteome Discovery in Cancers Using Ribosome Profiling and Proteogenomics
09:30–10:00 Lecture by Yardena Samuels, Challenges and Solutions in Effectively Targeting Neoantigens
10:00–10:30 Coffee Break
10:30–11:00 Lecture, Speaker/Title TBD
11:00–11:30 Lecture by Michal Bassani-Sternberg, Multi-omic Discovery of Non-canonical Immunopeptidome Sources: Challenges and Emerging Opportunities
11:30–12:00 Panel Discussion and Closing